PXD083923-1

PXD083923 is an original dataset announced via ProteomeXchange.

Title	Integrated DIA Proteomics of Tissue and Exudate Reveals Screening Markers for Early Detection of UC-Associated Cancer
Description	ulcerative colitis, colorectal cancer, Data-Independent Acquisition, bioinformatics analysis, Gene Ontology, Gene Set Enrichment AnalysisWe employed Data-Independent Acquisition (DIA)-based mass spectrometry to profile the proteomes of paired tissue and exudate samples from patients with UC and CRC. Differentially expressed proteins (DEPs) were analyzed using Gene Ontology (GO), KEGG, and Gene Set Enrichment Analysis (GSEA). Four candidate biomarkers, CDA, REG4, LCN2, and TNS1, were validated in serum samples using ELISA and receiver operating characteristic (ROC) curve analysis.
HostingRepository	iProX
AnnounceDate	2026-09-09
AnnouncementXML	Submission_2026-09-09_18:14:13.842.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jin Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2026-09-09 18:13:48	ID requested
⏵ 1	2026-09-09 18:14:16	announced

Dataset with its publication pending

submitter keyword: ulcerative colitis, colorectal cancer, Data-Independent Acquisition, bioinformatics analysis, Gene Ontology, Gene Set Enrichment Analysis

Jin Wang
contact affiliation	Tianjin Third Central Hospital
contact email	wangjane0917@126.com
lab head
Jin Wang
contact affiliation	Tianjin Third Central Hospital
contact email	wangjane0917@126.com
dataset submitter

iProX dataset URI