⮝ Full datasets listing
PXD082886-1
PXD082886 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LiP-MS analysis of punicalin-induced accessibility changes in respiratory syncytial virus F and G proteins |
| Description | This project contains the raw and processed limited proteolysis-mass spectrometry (LiP-MS) data generated to characterize punicalin-induced changes in the protease accessibility of recombinant respiratory syncytial virus (RSV) F and G proteins. Recombinant RSV F and G proteins were independently incubated with 10 μM punicalin or vehicle, with three biological replicates per condition, followed by limited proteolysis with proteinase K, tryptic digestion, and LC-MS/MS analysis using a timsTOF Pro mass spectrometer in data-dependent acquisition mode. Raw data were processed using FragPipe v22.0 with label-free quantification and match-between-runs enabled. The dataset includes instrument raw files, peptide and protein identification results, peptide abundance tables, search parameters, sequence databases, and the processed data used to identify PUN-responsive peptide regions. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-18 |
| AnnouncementXML | Submission_2026-08-20_03:43:37.917.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yingcai Xiong |
| SpeciesList | scientific name: Viruses; NCBI TaxID: 10239; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-20 03:41:16 | ID requested | |
| ⏵ 1 | 2026-08-20 03:43:38 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Respiratory syncytial virus, RSV, punicalin, LiP-MS, limited proteolysis-mass spectrometry, fusion protein, attachment glycoprotein, protein-ligand interaction, label-free quantification |
Contact List
| Jianjian Ji | |
|---|---|
| contact affiliation | Nanjing University of Chinese Medicine, Nanjing, China |
| contact email | jijj@njucm.edu.cn |
| lab head | |
| Yingcai Xiong | |
| contact affiliation | The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, China |
| contact email | yingcai_x@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
