PXD082855 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mapping the GW182 CIM1 binding site on CNOT1(800-999) by HDX-MS |
| Description | HDX-MS experiments were performed as described in detail in Białobrzewski M.K., Cieplak-Rotowska M.K., et al (https://www.biorxiv.org/content/10.64898/2026.07.16.738963v1) on human CNOT1 (residues 800-999) in the presence of peptides corresponding to GW182 CIM1 (QSRLPQWTHP), N-CIM1 (DPSQSQSRLPQWTHPN), the GW182 SD10 fragment (TNRC6C residues 1260-1620), or the TTP peptide (APRRLPIFNRISVSE). The interaction was additionally quantified by performing HDX-MS titrations of CNOT1(800-999) with increasing concentrations of the N-CIM1 peptide (0, 1.4, 3.5, 14, 70, 140, 280, and 700 µM). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-20 |
| AnnouncementXML | Submission_2026-08-20_03:06:49.965.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Agata Malinowska |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Synapt MS |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-19 11:20:41 | ID requested | |
| ⏵ 1 | 2026-08-20 03:06:50 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: CNOT1, HDX-MS |
Contact List
| Anna Niedzwiecka |
|---|
| contact affiliation | Institute of Physics, Polish Academy of Sciences, Warsaw, Poland |
| contact email | annan@ifpan.edu.pl |
| lab head | |
| Agata Malinowska |
|---|
| contact affiliation | IBB PAS |
| contact email | esme@ibb.waw.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD082855 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD082855
- Label: PRIDE project
- Name: Mapping the GW182 CIM1 binding site on CNOT1(800-999) by HDX-MS
