PXD082420-1

PXD082420 is an original dataset announced via ProteomeXchange.

Title	Study on the Mechanism of Qiwei Chanshen Granules in Inhibiting Colorectal Cancer through the PI3K/Akt Signaling Pathway Based on Multi-Omics and Experimental Validation
Description	In this study, human colorectal cancer HCT116 cells were used as the research model. Quantitative proteomics technology was applied to systematically analyze the protein expression profiles after QWCS treatment. Differentially expressed proteins were screened and subjected to functional enrichment and protein-protein interaction network analysis. This study aims to reveal potential therapeutic targets and key signaling pathways through which QWCS inhibits the proliferation and migration of HCT116 cells at the molecular level, providing proteomic evidence for further mechanistic research and clinical application of QWCS against colorectal cancer.
HostingRepository	iProX
AnnounceDate	2026-08-11
AnnouncementXML	Submission_2026-08-11_19:58:06.324.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Keyun Zhou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2026-08-11 19:57:18	ID requested
⏵ 1	2026-08-11 19:58:06	announced

Dataset with its publication pending

submitter keyword: Proteomics, QWCS, Colorectal Cancer, HCT116 Cells, Differentially Expressed Proteins, Signaling Pathway, Anticancer Mechanism

Xianqin Luo
contact affiliation	Chongqing Medical University
contact email	lxq_0203@163.com
lab head
Keyun Zhou
contact affiliation	Chongqing Medical University
contact email	august02z@163.com
dataset submitter

iProX dataset URI