PXD082146 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Legionella effector RavH is a tandem WH2-like domain-containing PI(3)P-dependent actin nucleator |
| Description | To decipher the mechanisms by which RavH modulates F-actin structures, we performed an affinity purification based SILAC (Stable Isotope Labeling with Amino Acids in Cell Culture) coupled mass spectrometry (MS)toidentify RavH-associated proteins. Cells expressing GFP-RavH or GFP alone were subjected to GFP immunoprecipitation, followed by quantitative MS analysis. We found that beta-actin was highly enriched when GFP-RavH was used as bait. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-14 |
| AnnouncementXML | Submission_2026-08-14_07:45:03.234.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Mateusz Wagner |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | 6x(13)C; 6x(13)C; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-04 08:12:21 | ID requested | |
| ⏵ 1 | 2026-08-14 07:45:03 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, SILAC, IP,Legionella |
Contact List
| Yuxin Mao |
|---|
| contact affiliation | Weill Institute for Cell and Molecular Biology. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA |
| contact email | ym253@cornell.edu |
| lab head | |
| Mateusz Wagner |
|---|
| contact affiliation | Weill Institute for Cell and Molecular Biology;
Biochemistry, Molecular and Cell Biology;
Cornell University |
| contact email | mmw249@cornell.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD082146 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD082146
- Label: PRIDE project
- Name: Legionella effector RavH is a tandem WH2-like domain-containing PI(3)P-dependent actin nucleator
