PXD080054 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of human NCOA7-AS binding partners |
| Description | The interferon inducible isoform of human NCOA7 (NCOA7-AS, for Alternative Start) is a TLDc protein that has been shown to be antiviral against influenza A virus and to interact with cytoplasmic subunits of the V-ATPase. Upon its ectopic expression, there is a decrease in endolysosomal pH that seems detrimental to the virus. In order to gain further light into NCOA7-AS mechanism of action, we have performed co-immunoprecipitation experiments (using triple flag tagged NCOA7-AS in U87-MG cells as well untagged NCOA7-AS as a control) and mass spectrometry analysis. Of note, U87-MG cells were used as they are easy to transduce with lentiviral vectors and express high levels of NCOA7-AS. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-27 |
| AnnouncementXML | Submission_2026-08-27_05:57:30.284.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Functional Proteomics Platform FPP |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-23 05:51:48 | ID requested | |
| ⏵ 1 | 2026-08-27 05:57:30 | announced | |
Publication List
Keyword List
| submitter keyword: Human, U87-MG cells, NCOA7-AS ISG |
Contact List
| Caroline Goujon |
|---|
| contact affiliation | IRIM (Institut de Recherche en Infectiologie de Montpellier), Université de Montpellier, CNRS, France |
| contact email | caroline.goujon@irim.cnrs.fr |
| lab head | |
| Functional Proteomics Platform FPP |
|---|
| contact affiliation | FPP CNRS |
| contact email | contact@fpp.cnrs.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD080054 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD080054
- Label: PRIDE project
- Name: Identification of human NCOA7-AS binding partners
