PXD077570-1

PXD077570 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of multiple neural and peripheral tissues in a mouse model of trigeminal neuralgia
Description	This project aims to characterize the proteomic alterations in four significant tissues—liver, infraorbital nerve, trigeminal ganglion, and spinal trigeminal nucleus caudalis—in a mouse model of trigeminal neuralgia induced by partial infraorbital nerve ligation (pIONL). Using a label-free quantitative proteomics approach, we compared pIONL mice with sham-operated controls. The data provide tissue-specific protein expression signatures associated with peripheral nerve injury, central pain processing, and systemic metabolic responses.
HostingRepository	iProX
AnnounceDate	2026-04-24
AnnouncementXML	Submission_2026-04-26_17:59:48.028.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chaoli Hong
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 6600

Revision	Datetime	Status	ChangeLog Entry
0	2026-04-24 00:05:27	ID requested
⏵ 1	2026-04-26 17:59:48	announced

Dataset with its publication pending

submitter keyword: Trigeminal neuralgia, partial infraorbital nerve injury, proteomics, trigeminal ganglion, infraorbital nerve, spatial trigeminal nucleus caudalis, liver, mouse model

Chaoli Hong
contact affiliation	Department of Endodontics, Zhonglou Branch, Changzhou Hospital of Traditional Chinese Medicine, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine
contact email	hongchl3@outlook.com
lab head
Chaoli Hong
contact affiliation	Changzhou Hospital of Traditional Chinese Medicine, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine
contact email	hongchl3@outlook.com
dataset submitter

iProX dataset URI