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PXD075650-1

PXD075650 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThermal Proteome Profiling of Small-Molecule-Treated THP-1 Cells
DescriptionThis project performed Thermal Proteome Profiling (TPP) on THP‑1 human monocytic cells to identify cellular protein targets and interactome profiles modulated by a small‑molecule compound. Quantitative proteomic analysis was conducted to detect protein stability changes upon compound treatment, aiming to reveal its molecular mechanism of action and potential therapeutic targets in immune‑related cellular models.
HostingRepositoryiProX
AnnounceDate2026-03-14
AnnouncementXMLSubmission_2026-03-15_23:41:00.848.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZiwen Feng
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-03-15 23:40:15ID requested
12026-03-15 23:41:01announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: STING inhibitor
Contact List
Xiaoli Xu
contact affiliationchina pharmaceutical university
contact emailxuxiao_li@126.com
lab head
Ziwen Feng
contact affiliationChina Pharmaceutical University
contact emailfzw0918@126.com
dataset submitter
Full Dataset Link List
iProX dataset URI