PXD074893 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mouse serum DIA-based proteomic profiling after 1-day or 7-day daily heat stress exposure |
| Description | This project profiles heat stress (HS)-induced alterations in the mouse serum proteome to identify circulating proteins that are consistently regulated by HS. Mice were assigned to three groups: PF (pair-fed control at room temperature, RT), HS1D (daily HS for 1 day, 6 h/day), and HS7D (daily HS for 7 consecutive days, 6 h/day). The PF group serves as the shared control and was collected at the same time point as the HS1D group (RT, 1 day), providing a reference for HS-associated changes. The primary objective is to identify overlapping proteomic changes in both HS groups relative to PF, highlighting robust HS-responsive circulating proteins. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-28 |
| AnnouncementXML | Submission_2026-04-27_22:10:31.699.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xu Feng |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-02-25 05:23:31 | ID requested | |
| ⏵ 1 | 2026-04-27 22:10:32 | announced | |
Publication List
| Zhou HY, Feng X, Wen J, Xiao Y, Wang LW, Chen LY, Xie GQ, Zhao JJ, Huang Y, Luo XH, A skin-hypothalamus axis couples heat stress and metabolic dysfunction. Cell, ():(2026) [pubmed] |
| 10.1016/j.cell.2026.03.045; |
Keyword List
| submitter keyword: mouse serum |
| DIA proteomics |
Contact List
| Xiang-Hang Luo |
|---|
| contact affiliation | Department of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University |
| contact email | xianghangluo@sina.com |
| lab head | |
| Xu Feng |
|---|
| contact affiliation | Xiangya Hospital of Central South University |
| contact email | fengxures@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD074893 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD074893
- Label: PRIDE project
- Name: Mouse serum DIA-based proteomic profiling after 1-day or 7-day daily heat stress exposure
