PXD073763 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Assessing the temporal proteomic changes in cancer cells surviving cisplatin or docetaxel treatment |
| Description | The goal of this project was to observe proteomic differences between cancer cells surviving chemotherapy (1-, 5-, and 10-Days post-treatment removal) and untreated parental cells. This provides us with a top-down view of pathways that could be enriched/down-regulated throughout those timepoints when compared to untreated parental cells and allow us to generate hypotheses to start new projects. The PC3 and MDA-MB-231 cell lines were used in this study. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-08 |
| AnnouncementXML | Submission_2026-06-07_16:09:13.725.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD073763 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Sarah Amend |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-01-29 04:24:36 | ID requested | |
| ⏵ 1 | 2026-06-07 16:09:14 | announced | |
Publication List
| Li M, Priem B, Loftus LV, Betenbaugh MJ, Pienta KJ, Amend SR, Polyploid cancer cells surviving cisplatin reallocate central carbon sources to fuel antioxidant metabolism for survival. Mol Metab, 108():102370(2026) [pubmed] |
| 10.1016/j.molmet.2026.102370; |
| 10.6019/PXD073763; |
Keyword List
| submitter keyword: breast cancer, therapy resistance,Prostate cancer |
Contact List
| Sarah Amend |
|---|
| contact affiliation | School of Medicine Johns Hopkins University Baltimore, MD 21287, USA |
| contact email | Samend2@jhmi.edu |
| lab head | |
| Sarah Amend |
|---|
| contact affiliation | Johns Hopkins University |
| contact email | samend2@jhmi.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD073763 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD073763
- Label: PRIDE project
- Name: Assessing the temporal proteomic changes in cancer cells surviving cisplatin or docetaxel treatment
