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PXD071688-1

PXD071688 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTime-resolved lung proteome profiling in an LPS-induced acute lung injury mouse model
DescriptionThis project investigates the dynamic lung proteome in a murine model of lipopolysaccharide (LPS)-induced acute lung injury (ALI). C57BL/6N mice were exposed to LPS via intratracheal nebulization to induce ALI, and lung tissues were collected at multiple time points (non-stimulated controls, and days 1, 3, 7 and 14 after LPS challenge) to capture the onset, peak and resolution phases of lung injury.
HostingRepositoryiProX
AnnounceDate2025-12-06
AnnouncementXMLSubmission_2026-02-24_17:14:09.868.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGuoan Xiang
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-07 18:12:40ID requested
12026-02-24 17:14:10announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LPS challenge, ALI, DIA proteomics
Contact List
Lixin Xie
contact affiliationCollege of Pulmonary & Critical Care Medicine, the Eighth Medical Center of Chinese PLA General Hospital
contact emaillxxie@126.com
lab head
Guoan Xiang
contact affiliationCollege of Pulmonary & Critical Care Medicine, the Eighth Medical Center of Chinese PLA General Hospital
contact emailxiangguoan2021@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI