PXD070950-1

PXD070950 is an original dataset announced via ProteomeXchange.

Title	Lyso-IP from Wdr7 iKO MEFs .
Description	Lysosomes were enriched from Wdr7 iKO MEFs stably expressing TMEM192-3xHA (Bait) or TMEM192-2xFlag (Ctrl) via lysosomal immunoprecipitation (Lyso-IP) using PierceTM anti-HA magnetic beads to analyze changes in the lysosomal protein content upon induced depletion of Wdr7.
HostingRepository	PRIDE
AnnounceDate	2026-06-25
AnnouncementXML	Submission_2026-06-24_22:50:27.460.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wilhelm Palm
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-19 11:30:20	ID requested
⏵ 1	2026-06-24 22:50:27	announced

10.1038/S44318-026-00838-5;

submitter keyword: Lyso-IP, MEFs, V-ATPase, Tmem192, lysosomes, iKO, Wdr7

Dr. Wilhelm Palm
contact affiliation	German Cancer Research Center (DKFZ) Cell Signaling and Metabolism Division Head
contact email	w.palm@dkfz-heidelberg.de
lab head
Wilhelm Palm
contact affiliation	German Cancer Research Center (DKFZ)
contact email	w.palm@dkfz-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD070950

PRIDE project URI

• PRIDE
  1. PXD070950
     1. Label: PRIDE project
     2. Name: Lyso-IP from Wdr7 iKO MEFs