PXD069668 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Structural proteomics reveals that misfolded nascent proteins expose buried lysines for ubiquitination and rapid proteasomal degradation |
| Description | In this study, we combine structural proteomics and time-resolved isotopic labeling to profile the modification sites, dynamics, and conformational properties of the human ubiquitinome. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-25 |
| AnnouncementXML | Submission_2026-06-24_21:44:34.958.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Anushka Jain |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | 6x(13)C labeled L-lysine; L-methionine sulfoxide; 6x(13)C; ubiquitination signature dipeptidyl lysine; 6x(13)C labeled L-arginine |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-20 07:41:01 | ID requested | |
| 1 | 2026-04-27 14:21:00 | announced | |
| ⏵ 2 | 2026-06-24 21:44:35 | announced | 2026-06-25: Updated project metadata. |
Publication List
Keyword List
Contact List
| Sina Ghaemmaghami |
|---|
| contact affiliation | Ghaemmaghami Lab, Department of Biology, University of Rochester, NY, US |
| contact email | sina.ghaemmaghami@rochester.edu |
| lab head | |
| Anushka Jain |
|---|
| contact affiliation | University of Rochester |
| contact email | anushka.jain@rochester.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD069668 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069668
- Label: PRIDE project
- Name: Structural proteomics reveals that misfolded nascent proteins expose buried lysines for ubiquitination and rapid proteasomal degradation
