PXD068439 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Cardiac Proteomic and Phosphoproteomic Profiling Identifies Molecular Sources of Heterogeneity in Human Heart Failure. |
| Description | To provide comprehensive characterization of the cardiac proteome of advanced human heart failure, we performed mass spectrometry-based label free proteomic analysis of left ventricular samples obtained from 149 human heart failure patients and 9 non-failing controls. All heart failure biopsy samples were collected at the time of heart transplantation or assist device implantation. To characterize signaling perturbations, we performed phosphoproteomic analysis for 32 representative heart failure samples and 8 non-failing controls. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-22 |
| AnnouncementXML | Submission_2026-08-21_19:19:12.265.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Omar Hamed |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-09-16 23:59:00 | ID requested | |
| ⏵ 1 | 2026-08-21 19:19:12 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, Phosphoproteomics, Heart Failure, Proteomics |
Contact List
| Anthony Gramolini |
|---|
| contact affiliation | Department of Physiology and Translational Biology and Engineering Program Temerty Faculty of Medicine University of Toronto |
| contact email | anthony.gramolini@utoronto.ca |
| lab head | |
| Omar Hamed |
|---|
| contact affiliation | Temerty Faculty of Medicine - University of Toronto |
| contact email | omar.hamed@utoronto.ca |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD068439 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD068439
- Label: PRIDE project
- Name: Cardiac Proteomic and Phosphoproteomic Profiling Identifies Molecular Sources of Heterogeneity in Human Heart Failure.
