PXD066861 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative mass spectrometry reveals a novel TTC33-associated network core (TANC) complex with functions in DNA damage response |
| Description | TTC33 is a 30 kDa human uncharacterized tetratricopeptide repeat protein. Here, we employed label-free mass spectrometry analysis to identify the proteins interactors. The TTC33-associated network (TAN) is composed of WDR61, PHF5A, which together with TTC33 form a trimeric core complex (TANC), that recruits UNG1/2 DNA glycosylase, uncharacterized CCDC97, SF3B, a sub-complex of U2-splicing factor, and PP2A phosphatase (PPP2R1A, PPP2CA/CB and PPP2R2A). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-06 |
| AnnouncementXML | Submission_2026-07-06_05:42:19.772.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD066861 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Agata Malinowska |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | methylthiolated residue; monohydroxylated residue |
| Instrument | Orbitrap Astral; Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-01 06:04:31 | ID requested | |
| ⏵ 1 | 2026-07-06 05:42:20 | announced | |
Publication List
Keyword List
| submitter keyword: TTC33, DNA repair, WDR61, PAFc,UNG DNA glycosylase, SKIc, PHF5A |
Contact List
| Agnieszka Tudek |
|---|
| contact affiliation | Laboratory of RNA Processing and Decay, Institute of Biochemistry and Biophysics, Warsaw, Poland |
| contact email | atudek@ibb.waw.pl |
| lab head | |
| Agata Malinowska |
|---|
| contact affiliation | IBB PAS |
| contact email | esme@ibb.waw.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD066861 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066861
- Label: PRIDE project
- Name: Comparative mass spectrometry reveals a novel TTC33-associated network core (TANC) complex with functions in DNA damage response
