PXD066054-1

PXD066054 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	General proteomics and lactylation-modified proteomics were used to detect 5 cases of prostate cancer tissues and 5 cases of benign prostatic hyperplasia tissues
Description	Proteomic sequencing was performed on 5 prostate cancer patient tissues and 5 benign prostatic hyperplasia patient tissues collected from Beijing Tongren Hospital Affiliated to Capital Medical University. Differential genes related to the prognosis of prostate cancer were identified, and enrichment analysis was conducted on prostate cancer patients based on these genes to clarify the biological functions in prostate cancer cells that significantly affect cancer cell progression. Lactylation modification proteomic sequencing revealed the sites in prostate cancer that promote prostate cancer progression due to lactylation modification, providing potential therapeutic methods for the treatment of prostate cancer.
HostingRepository	PRIDE
AnnounceDate	2026-01-23
AnnouncementXML	Submission_2026-01-23_02:33:38.182.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	zou fan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro 2

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-11 04:29:49	ID requested
⏵ 1	2026-01-23 02:33:39	announced

Publication List

10.1186/s12967-025-06990-6;
Zou F, Jin Y, Zhang Z, Zhang Y, Wang M, Zhu F, Qiu J, Ye H, Fu Y, Ping H, Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics. J Transl Med, 23(1):967(2025) [pubmed]

10.1186/s12967-025-06990-6;

Zou F, Jin Y, Zhang Z, Zhang Y, Wang M, Zhu F, Qiu J, Ye H, Fu Y, Ping H, Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics. J Transl Med, 23(1):967(2025) [pubmed]

Keyword List

submitter keyword: Human
PCa
BPH
Lactylation

submitter keyword: Human

PCa

BPH

Lactylation

Contact List

Fan Zou
contact affiliation	Beijing Tongren Hospital, Capital Medical University
contact email	15107246146@163.com
lab head
zou fan
contact affiliation	capital medical university
contact email	15107246146@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD066054
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD066054

PRIDE project URI

Repository Record List

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