PXD064903-1

PXD064903 is an original dataset announced via ProteomeXchange.

Title	In vitro activity of quisinostat against Toxoplasma gondii
Description	We performed quisinostat drug bath on Toxoplasma gondii RH strain. Next, we carried out research using data-independent acquisition (DIA) quantitative proteomics technology. A total of 4,243 proteins were identified in the four samples, all of which were quantifiable. Proteins with significant differential expression were screened based on the criteria of fold change ≥1.5 (up-regulation >1.5-fold or down-regulation <0.67-fold) and P value <0.05. Among them, 282 proteins showed significant changes in expression levels, with 77 proteins significantly up-regulated and 205 proteins significantly down-regulated. Based on the above data, systematic bioinformatics analysis was conducted for all identified proteins.
HostingRepository	iProX
AnnounceDate	2025-06-11
AnnouncementXML	Submission_2025-06-11_19:37:45.297.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chunxue Zhou
SpeciesList	scientific name: Toxoplasma gondii RH; NCBI TaxID: 383379;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-11 19:37:32	ID requested
⏵ 1	2025-06-11 19:37:45	announced

Dataset with its publication pending

submitter keyword: Toxoplasma gondii, quisinostat, proteome

Chunxue Zhou
contact affiliation	Shandong University
contact email	zhouchunxue23@163.com
lab head
Chunxue Zhou
contact affiliation	Shandong University
contact email	zhouchunxue23@163.com
dataset submitter

iProX dataset URI