PXD062946-1

PXD062946 is an original dataset announced via ProteomeXchange.

Title	Identification of interactors of the Drosophila zinc finger protein hangover
Description	The Drosophila melanogaster multi zinc finger protein hangover (hang) regulates responses to oxidative stress, heat shock and ethanol exposure by modulating transcript levels in adult fly heads. The hangover protein contains no less than 18 C2H2-type zinc fingers. These domains are prevalent among chromatin-regulating proteins, particularly transcription factors, where they typically mediate associations with DNA and transcriptional effectors. Here, we identify hangover-interacting proteins in order to shed light on its molecular function.
HostingRepository	PRIDE
AnnounceDate	2025-12-22
AnnouncementXML	Submission_2025-12-21_16:19:16.008.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ignasi Forne
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: NEWT:7227;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-14 12:12:29	ID requested
⏵ 1	2025-12-21 16:19:16	announced

Lenz J, Schmelzer L, Forn, é I, Nist A, Imhof A, Stiewe T, Brehm A, Hangover regulates gene expression by limiting NSL-mediated H4K16 acetylation. Nucleic Acids Res, 53(22):(2025) [pubmed]

10.1093/nar/gkaf1349;

submitter keyword: transcription factor,hangover, chromatin

Prof. Dr. Alexander Brehm
contact affiliation	Institute of Molecular Biology and Tumor Research, Biomedical Research Center, Philipps-University, Marburg, Hans-Meerwein-Str. 2 35043 Marburg (Germany).
contact email	brehm@imt.uni-marburg.de
lab head
Ignasi Forne
contact affiliation	Biomedical Center-LMU
contact email	ignasi.forne@lrz.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD062946

PRIDE project URI

• PRIDE
  1. PXD062946
     1. Label: PRIDE project
     2. Name: Identification of interactors of the Drosophila zinc finger protein hangover