PXD062926-1

PXD062926 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ser2 phospholyration is suppressed by 7SK snRNA on snRNA for accurate termination. The mass data set of ICE1::AFF4 and ICE1 IP.
Description	We prepared nuclear extracts from three types of HeLa cells: those expressing ICE1::AFF4, ICE1 alone, and untransduced control cells. Using V5-tag immunoprecipitation (IP), we aimed to compare the proteins associated with ICE1 and ICE1::AFF4. Our hypothesis is that the ICE1::AFF4 fusion protein will pull down more components of the Super Elongation Complex (SEC) than ICE1 alone, indicating enhanced interaction due to the presence of AFF4. This would suggest that AFF4 promotes SEC recruitment when fused to ICE1, potentially modulating transcriptional elongation.
HostingRepository	jPOST
AnnounceDate	2025-06-12
AnnouncementXML	Submission_2025-06-11_14:36:57.795.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ogawa Shintaro
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-14 04:39:41	ID requested
⏵ 1	2025-06-11 14:36:58	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: ICE1::AFF4

submitter keyword: ICE1::AFF4

Contact List

Hidehisa Takahashi
lab head
Ogawa Shintaro
contact affiliation	Yokohama City University Dept of Morecularbiology
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003751/