PXD062916 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Association of heme-bound HRI with S-DELE1 promotes HRI auto-phosphorylation |
| Description | This dataset assesses the effects of S-DELE1 association on the auto-phosphorylation of human, heme-bound HRI. Human HRI and DELE1 were expressed in EIF2alpha-phospho-resistant cells supplemented with hemin. HRI was affinity purified, the elution subjected to denaturing gel electrophoresis, and HRI phosphorylation was assessed by MS. The data set identifies S-DELE1 induced phosphorylation sites in the N-terminal domain of HRI, its two kinase domains, and the kinase insert. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-09 |
| AnnouncementXML | Submission_2026-06-09_01:53:00.371.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lara Rheinemann |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-14 01:44:24 | ID requested | |
| ⏵ 1 | 2026-06-09 01:53:00 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
Contact List
| Andreas Pichlmair |
|---|
| contact affiliation | Institute of Virology - Viral Immunopathology, Faculty of Medicine, Technical University Munich |
| contact email | andreas.pichlmair@tum.de |
| lab head | |
| Lara Rheinemann |
|---|
| contact affiliation | Institute of Virology
Technical University Munich |
| contact email | lara.rheinemann@tum.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD062916 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062916
- Label: PRIDE project
- Name: Association of heme-bound HRI with S-DELE1 promotes HRI auto-phosphorylation
