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PXD062707-1

PXD062707 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic and Acetylome Alterations in Obesity-related Osteoarthritic Mouse Cartilage
Description	Male mice aged 4 weeks were housed under controlled conditions and assigned to either a normal diet or a high-fat diet for 16 weeks to establish an obesity model. At 12 weeks, osteoarthritis was induced using the destabilization of the medial meniscus procedure under anesthesia, while sham-operated mice served as controls. Eight weeks post-surgery, tibial cartilage tissues were collected, ensuring surrounding tissues were removed under a microscope. Tissues from 3-5 mice per group were pooled, and flash-frozen for subsequent lipidomic, proteomic, and acetylome analyses.
HostingRepository	iProX
AnnounceDate	2025-04-08
AnnouncementXML	Submission_2025-04-08_00:17:09.598.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shuying Shen
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	acetylated residue
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-08 00:16:54	ID requested
⏵ 1	2025-04-08 00:17:09	announced
2	2025-07-06 20:46:31	announced	2025-07-07: Add info.

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: Proteomic, Acetylome

Contact List

Shunwu Fan
contact affiliation	Sir Run Run Shaw Hospital, Zhejiang University School of Medicin
contact email	shunwu_fan@zju.edu.cn
lab head
Shuying Shen
contact affiliation	Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
contact email	11207057@zju.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI