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PXD062248-1

PXD062248 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeting CPXM2-DSD enhances the sensitivity of PDAC treatment by disrupting collagen fiber alignment
Description5×106 PaTu 8988t cells were spread into 10cm dish and then replaced into 5ml serum-free medium after being attached to the wall. At the same time, 5ml of the supernatant of PCAF-Ctrl, PCAF-CPXM2-WT and PCAF-CPXM2-mut stable cell strains were added to each group. After 8 hours, proteins from each group were collected for phosphorylated protein enrichment. The phosphorylated protein enrichment kit was used for this process, followed by protein mass spectrometry analysis of the signaling pathway of pancreatic cancer cells activated by collagen topology mediated by CPXM2.
HostingRepositoryiProX
AnnounceDate2025-03-26
AnnouncementXMLSubmission_2025-12-03_17:21:00.775.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSuoyu Xiang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-03-26 00:15:39ID requested
12025-12-03 17:21:01announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: CPXM2 aligning, PaTu cells
Contact List
Jun Mi
contact affiliationShanghai Jiao Tong University, School of Medicine
contact emailjmei@sjtu.edu.cn
lab head
Suoyu Xiang
contact affiliationShanghai Jiao Tong University, School of Medicine
contact emailxiangsuoyu@sjtu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI