⮝ Full datasets listing
PXD062062-1
PXD062062 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Structural-guided identification of two novel modulators of β-1,3-glucan synthase FKS1 |
| Description | FKS1 is a β-1,3-glucan synthase that plays a critical role in fungal cell wall formation and serves as a key target for antifungal drugs such as echinocandin and ibrexafungerp. However, the molecular mechanisms regulating FKS1 activity remain largely unknown. This study identifies its endogenous inhibitor and stabilizing factor |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-20 |
| AnnouncementXML | Submission_2026-06-01_19:23:49.523.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jialu Li |
| SpeciesList | scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-19 23:45:32 | ID requested | |
| ⏵ 1 | 2026-06-01 19:23:50 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: YMR295C，β-1,3-glucan synthase，FKS1 |
Contact List
| Xiang Wang | |
|---|---|
| contact affiliation | West China Second University Hospital，Sichuan University |
| contact email | xiangwang@scu.edu.cn |
| lab head | |
| Jialu Li | |
| contact affiliation | West China Second University Hospital，Sichuan University |
| contact email | lijl@scu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
