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PXD059955-1

PXD059955 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Heat shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux
Description	HEK293T cells were transfected with GFP-poly-G-TurboID or GFP-TurboID as a control. Following biotin labelling, the cells were lysed in RIPA buffer to separate the soluble and insoluble fractions. The insoluble proteins in the pellet containing poly-G aggregates were further lysed in the lysis buffer containing 8 M urea to ensure effective solubilization
HostingRepository	iProX
AnnounceDate	2025-01-20
AnnouncementXML	Submission_2025-01-19_23:44:02.101.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ning Ding
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-19 23:43:48	ID requested
⏵ 1	2025-01-19 23:44:02	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: turbo-GFP-G100, turbo-GFP

Contact List

Lei Li
contact affiliation	ShanghaiTech University
contact email	lilei@shanghaitech.edu.cn
lab head
Ning Ding
contact affiliation	ShanghaiTech University
contact email	2206609605@qq.com
dataset submitter

Full Dataset Link List

iProX dataset URI