PXD059578-1
PXD059578 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Chronic stress-induced cholesterol metabolism abnormalities promote ESCC tumorigenesis and predict neoadjuvant therapy response |
| Description | chronic stress activates the GCR-HMGB2-LDLR axis via cortisol release, leading to abnormal cholesterol metabolism and ultimately promoting esophageal carcinogenesis |
| HostingRepository | iProX |
| AnnounceDate | 2025-01-09 |
| AnnouncementXML | Submission_2025-01-08_23:49:29.075.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ting Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | 4800 Plus MALDI TOF/TOF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-01-08 23:49:13 | ID requested | |
| ⏵ 1 | 2025-01-08 23:49:29 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: ESCC,Chronic stress, Cortisol, GCR, HMGB2, LDLR, Cholesterol |
Contact List
| Zigang Dong | |
|---|---|
| contact affiliation | School of Basic Medical Sciences, Zhengzhou University |
| contact email | dongzg@zzu.edu.cn |
| lab head | |
| Ting Wang | |
| contact affiliation | School of Basic Medical Sciences, Zhengzhou University |
| contact email | twang@hci-cn.org |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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