PXD059411-1

PXD059411 is an original dataset announced via ProteomeXchange.

Title	Pancreatic cancer Serpinb9（KD VS NC) proteomics
Description	This study investigates the proteomic alterations in pancreatic cancer cells resulting from Serpinb9 knockdown (KD) compared to normal control (NC). Two experimental groups, each consisting of three biological replicates, were analyzed to identify key proteins and pathways associated with Serpinb9's role in pancreatic cancer. Protein identification and quantification were performed using high-resolution mass spectrometry to provide insights into molecular mechanisms underlying its biological function
HostingRepository	PRIDE
AnnounceDate	2025-09-01
AnnouncementXML	Submission_2025-08-31_16:30:05.813.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hanshen Yang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-03 01:40:45	ID requested
⏵ 1	2025-08-31 16:30:06	announced

Yang H, Zhang X, Zhang S, Yang Y, Chen Y, Jiang Y, Lu Q, Liu L, Lao M, Du W, Sun K, He L, Shi J, Liu X, Song J, Lu N, Huang J, Huang J, Zhou R, Lu X, Liang T, Bai X, Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer. Nat Commun, 16(1):7827(2025) [pubmed]

10.1038/s41467-025-63146-2;

submitter keyword: Serpinb9,Pancreatic cancer, knockdown

Hanshen Yang
contact affiliation	The First Affiliated Hospital, School of Medicine, Zhejiang University
contact email	hanshenyang@zju.edu.cn
lab head
Hanshen Yang
contact affiliation	The First Affiliated Hospital, School of Medicine, Zhejiang University
contact email	hanshenyang@zju.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD059411

PRIDE project URI

• PRIDE
  1. PXD059411
     1. Label: PRIDE project
     2. Name: Pancreatic cancer Serpinb9（KD VS NC) proteomics