PXD058131-1

PXD058131 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics and metabolomics of different delivery modes in human pregnancy
Description	This project investigates the impact of different delivery modes and labor on maternal and neonatal health by analyzing 40 participants, including 16 spontaneous vaginal deliveries (VD), 16 prelabor cesarean deliveries (CS), and 8 intrapartum cesarean sections (Intra_CS). Using label-free proteomics and untargeted metabolomics, both amniotic fluid and cord blood samples were analyzed respectively to identify variations in protein and metabolite profiles associated with the mode of delivery. The study aims to uncover biological pathways influenced by labor and delivery mode, providing insights into how these factors shape maternal and neonatal outcomes, with implications for improving perinatal care and long-term health strategies.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_05:36:23.511.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yun Huang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-21 04:18:45	ID requested
⏵ 1	2025-05-07 05:36:24	announced

Publication List

Huang Y, Ni Y, Meng Y, Zeng X, He X, Zhang L, Zhang J, Integrated proteomics and metabolomics network analysis across different delivery modes in human pregnancy: a pilot study. BMC Pregnancy Childbirth, 24(1):868(2024) [pubmed]
10.1186/s12884-024-07097-4;

Huang Y, Ni Y, Meng Y, Zeng X, He X, Zhang L, Zhang J, Integrated proteomics and metabolomics network analysis across different delivery modes in human pregnancy: a pilot study. BMC Pregnancy Childbirth, 24(1):868(2024) [pubmed]

10.1186/s12884-024-07097-4;

Keyword List

submitter keyword: Proteomics
metabolomics
delivery modes

submitter keyword: Proteomics

metabolomics

delivery modes

Contact List

Yun Huang
contact affiliation	Jun Jim Zhangjunjimzhang@sjtu.edu.cnMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
contact email	yunhuang.pku@gmail.com
lab head
Yun Huang
contact affiliation	Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
contact email	yunhuang.pku@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD058131
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD058131

PRIDE project URI

Repository Record List

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