PXD056850-1

PXD056850 is an original dataset announced via ProteomeXchange.

Title	Warming and polymetallic stress induce proteomic and physiological shifts in the neurotoxic Alexandrium pacificum as possible response to global changes.
Description	Harmful Algal Blooms involving the dinoflagellate Alexandrium pacificum continue to increase in marine ecosystems suffering the climate warming and anthropogenic pressure. Proteomics may contribute to better understand the responses of organisms exposed to environmental stress, thanks to the identification of stress proteins modified in their expression under such conditions. These proteins of interest can be enzymes involved in the regulation of metabolic pathways associated with adaptive proteomic response of an organism to face stresses. Present in mediterranean anthropized coastal ecosystems suffering the global warming, Alexandrium is a biological model of interest for studying the effects of global changes. To our knowledge and to date, no study has been carried out on the proteomic response of A. pacificum to global changes, such as warming and trace metal pollution. As a result, to enhance our understanding of this HAB species responses to the ongoing global changes, the present study aims at characterizing its proteomic and physiological (growth kinetics, morphometric measurements and PSTs) shifts under disturbed environmental conditions, i.e. using a mediterranean strain of A. pacificum successively exposed at 24°C, 27°C or 30°C, with or without polymetallic stress.
HostingRepository	PRIDE
AnnounceDate	2026-09-01
AnnouncementXML	Submission_2026-09-01_09:18:44.444.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thierry Balliau
SpeciesList	scientific name: Alexandrium pacificum; NCBI TaxID: NEWT:1565494;
ModificationList	(R)-5-oxo-1; 2-pyrrolidone-5-carboxylic acid (Glu); 2-pyrrolidone-5-carboxylic acid (Gln); acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-16 04:07:08	ID requested
⏵ 1	2026-09-01 09:18:45	announced

10.1016/j.marpolbul.2024.117221;

Jean N, James A, Balliau T, Martino C, Ghersy J, Savar V, Laabir M, Caruana AMN, Warming and polymetallic stress induce proteomic and physiological shifts in the neurotoxic Alexandrium pacificum as possible response to global changes. Mar Pollut Bull, 209(Pt B):117221(2024) [pubmed]

submitter keyword: Alexandrium pacificum

harmful algal bloom

paralytic shellfish toxin

proteomics

global warming

trace metals.

Dr Natacha JEAN
contact affiliation	Université de Toulon, Aix Marseille Univ., CNRS, IRD, Mediterranean Institute of Oceanography (MIO), Toulon, France
contact email	natacha.jean@mio.osupytheas.fr
lab head
Thierry Balliau
contact affiliation	Plateforme d'Analyse Proteomique Paris Sud-Ouest Université Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE - Le Moulon, 91190, Gif-sur-Yvette, France
contact email	thierry.balliau@inrae.fr
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD056850
     1. Label: PRIDE project
     2. Name: Warming and polymetallic stress induce proteomic and physiological shifts in the neurotoxic Alexandrium pacificum as possible response to global changes.