PXD055761-1
PXD055761 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic studies of mechanism of action of apigenin in stromal cells by five proteomic experiments |
| Description | The present studies consist of five proteomic experiments: proteomic profiling treated by apigenin; DARTS coupled MS analysis to identify the potential directed proteins targets of apigenin; Identification of the potential directed protein targets of biotin-apigenin by pull-down coupled MS analysis; proteomic profiling of senescent cells upon treatment with MJ33; Identification of the proteins interacting with PRDX6 by Co-IP coupled MS analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2025-01-20 |
| AnnouncementXML | Submission_2025-09-03_00:26:59.879.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hongwei Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-09-09 23:16:25 | ID requested | |
| ⏵ 1 | 2025-09-03 00:27:00 | announced |
Publication List
| Zhang H, Xu Q, Jiang Z, Sun R, Wang Q, Liu S, Luan X, Campisi J, Kirkland JL, Zhang W, Sun Y, Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age-Related Conditions in Mice. Adv Sci (Weinh), 12(20):e2412950(2025) [pubmed] |
Keyword List
| submitter keyword: apigenin, proteomic profiling, protein targets, Co-IP, PRDX6, MJ33, LC-MS |
Contact List
| Yu Sun | |
|---|---|
| contact affiliation | CAS Key Laboratory of Tissue Microenvironment and Tumour, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China |
| contact email | sunyu@sinh.ac.cn |
| lab head | |
| Hongwei Zhang | |
| contact affiliation | Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China |
| contact email | 12021179@shutcm.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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