⮝ Full datasets listing
PXD054945-1
PXD054945 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Chlorogeni cacid compounds from sweetpotato (lpomoeabatatas L.) leaves facilitate megakaryocyte differentiationand thrombocytopoiesis via Pl3K/AkT pathway |
| Description | Idiopathic thrombocytopenic purpura (lTP) is anautoimmune disorder characterized by antiplateletautoantibodies, thrombocytopenia, and bleeding. In thisstudy, a kind of active component, chlorogenic acidcompounds(CGAs)from sweetpotato leaves was isolatedby ionic liquids-ultrasound, which contains 6 isomers ofchlorogenic acid with total purity of 95.69%. CGAs couldpromote platelet formation in a murine model of ITP, whichwas established by injection of antiplatelet antibody. Tocharacterize the impact of CGAs on the bone marrowproteome in mice, tissue samples were subjected toproteomic analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2024-08-15 |
| AnnouncementXML | Submission_2025-11-26_17:45:26.553.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yi Zhang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-08-15 20:26:32 | ID requested | |
| ⏵ 1 | 2025-11-26 17:45:27 | announced |
Publication List
| Zhang Y, Zhao L, Wang L, Yue R, Zhu H, Zhang W, Sun J, Zhang Z, Ma D, PI3K/AKT pathway. Front Pharmacol, 15():1414739(2024) [pubmed] |
Keyword List
| submitter keyword: sweetpotato leaves, chlorogenic acid compounds.idiopathic thrombocytopenic purpura |
Contact List
| Jian Sun | |
|---|---|
| contact affiliation | Jiangsu Normal University |
| contact email | zhangyijsnu@163.com |
| lab head | |
| Yi Zhang | |
| contact affiliation | Jiangsu Normal University |
| contact email | zhangyijsnu@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
