PXD054129-1
PXD054129 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics reveals the mechanism of Qingre Huo xue decoction in treating rheumatoid arthritis |
Description | Rheumatoid arthritis is an autoimmune disease characterized by chronic synovitis, which can lead to irreversible joint damage as well as cardiovascular and respiratory system damage. The Qingre Huoxue Decoction is a Chinese medicine compound that has been clinically proven to be effective in treating RA, but its mechanism has not yet been elucidated. This study identified 83 differentially expressed proteins, including 46 upregulated proteins and 37 downregulated proteins, through proteomic analysis of the serum of RA patients before and after 24 weeks of treatment with Qingre Huoxue Decoction and healthy human. Among them, FBP1 protein may be a potential therapeutic target of Qingre Huoxue Decoction. |
HostingRepository | iProX |
AnnounceDate | 2024-07-23 |
AnnouncementXML | Submission_2024-07-22_20:43:40.953.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Fuyuan Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-07-22 20:41:25 | ID requested | |
⏵ 1 | 2024-07-22 20:43:41 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Rheumatoid arthritis, Chinese Medicine, DIA proteomics, LC-MS/MS, Fructose-1,6-bisphosphatase |
Contact List
Jiang Quan | |
---|---|
contact affiliation | Guang'anmen Hospital of the Chinese Academy of Traditional Chinese Medicine |
contact email | doctorjq@126.com |
lab head | |
Fuyuan Zhang | |
contact affiliation | Guang'anmen Hospital of the Chinese Academy of Traditional Chinese Medicine |
contact email | doctorzfy@126.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |