⮝ Full datasets listing
PXD052980-2
PXD052980 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | STEAP3 promotes TNBC growth through the FGFR1-mediated activation of PI3K/AKT signaling |
| Description | Breast cancer cells were cultured and harvested for proteomic analysis. Cells were lysed using a buffer containing 8 M urea, and proteins were extracted by sonication. The lysate was centrifuged to remove debris, and the supernatant was collected. Protein concentration was determined using the BCA assay. Samples were then reduced with DTT, alkylated with IAA, and digested overnight with trypsin. Peptides were desalted using C18 columns before mass spectrometry analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2024-06-11 |
| AnnouncementXML | Submission_2025-12-10_01:04:49.419.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lifang Yuan |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-06-10 19:23:55 | ID requested | |
| 1 | 2024-06-10 19:25:09 | announced | |
| ⏵ 2 | 2025-12-10 01:04:50 | announced | 2025-12-10: Add info |
Publication List
| Yuan L, Bao Y, Liu J, Sun P, STEAP3 promotes triple-negative breast cancer growth through the FGFR1-mediated activation of PI3K/AKT/mTOR signaling. iScience, 28(6):112526(2025) [pubmed] |
Keyword List
| submitter keyword: STEAP3, TNBC, PI3K-AKT-mTOR, cell proliferation |
Contact List
| Lifang Yuan | |
|---|---|
| contact affiliation | Yantai Yuhuangding hospital, Shandong University |
| contact email | yuanlf2020@mail.sdu.edu.cn |
| lab head | |
| Lifang Yuan | |
| contact affiliation | Yantai Yuhuangding hospital, Shandong University |
| contact email | yuanlf2020@mail.sdu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
