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PXD052980-1

PXD052980 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSTEAP3 promotes TNBC growth through the FGFR1-mediated activation of PI3K/AKT signaling
DescriptionBreast cancer cells were cultured and harvested for proteomic analysis. Cells were lysed using a buffer containing 8 M urea, and proteins were extracted by sonication. The lysate was centrifuged to remove debris, and the supernatant was collected. Protein concentration was determined using the BCA assay. Samples were then reduced with DTT, alkylated with IAA, and digested overnight with trypsin. Peptides were desalted using C18 columns before mass spectrometry analysis.
HostingRepositoryiProX
AnnounceDate2024-06-11
AnnouncementXMLSubmission_2024-06-10_19:25:09.380.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLifang Yuan
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-10 19:23:55ID requested
12024-06-10 19:25:09announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: STEAP3, TNBC, PI3K-AKT-mTOR, cell proliferation
Contact List
Lifang Yuan
contact affiliationYantai Yuhuangding hospital, Shandong University,
contact emailyuanlf2020@mail.sdu.edu.cn
lab head
Lifang Yuan
contact affiliationYantai Yuhuangding hospital, Shandong University.
contact emailyuanlf2020@mail.sdu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI