PXD051101-1

PXD051101 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Investigating the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell
Description	GalNAc-T2 was identified as a novel antiviral factor that promotes viral clearance and contributes to reduced disease severity.This project aimed to investigate the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell. We employ SILAC labeling, lectin-based affinity enrichment, and LC-ETD MS/MS to characterize the regulated proteins and glycosylation sites resulting from GalNAc-T2 overexpression.
HostingRepository	PRIDE
AnnounceDate	2026-01-12
AnnouncementXML	Submission_2026-01-11_16:18:18.537.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuqi He
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; complex glycosylation; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-30 06:27:33	ID requested
⏵ 1	2026-01-11 16:18:19	announced

Publication List

Ran W, Yang J, Yu S, Hu Q, He Y, Wang S, Wei C, Sun J, Zhu A, Li F, Zhang L, Li P, Hu H, Pan R, Yu Y, Yuan Y, Sun L, Wang Y, Zhang Z, Chen Z, Liu D, Yan Q, Wang D, Yu K, Wang Y, Zhuo J, Zhuang Z, Tao H, Zeng Q, Zhou K, Chen F, Tang W, Zhou Y, Bai R, Xu Y, Li N, Dai J, Zhao H, Park JE, Wang T, Ding Q, Perlman S, Zhao J, Mao Y, Wang S, Zhao J, Interferon-stimulated gene GALNT2 restricts respiratory virus infections. Nat Microbiol, 11(1):256-270(2026) [pubmed]
10.1038/s41564-025-02200-7;

Ran W, Yang J, Yu S, Hu Q, He Y, Wang S, Wei C, Sun J, Zhu A, Li F, Zhang L, Li P, Hu H, Pan R, Yu Y, Yuan Y, Sun L, Wang Y, Zhang Z, Chen Z, Liu D, Yan Q, Wang D, Yu K, Wang Y, Zhuo J, Zhuang Z, Tao H, Zeng Q, Zhou K, Chen F, Tang W, Zhou Y, Bai R, Xu Y, Li N, Dai J, Zhao H, Park JE, Wang T, Ding Q, Perlman S, Zhao J, Mao Y, Wang S, Zhao J, Interferon-stimulated gene GALNT2 restricts respiratory virus infections. Nat Microbiol, 11(1):256-270(2026) [pubmed]

10.1038/s41564-025-02200-7;

Keyword List

submitter keyword: GalNAc-T2, glycoproteomics, lung, Homo sapiens

submitter keyword: GalNAc-T2, glycoproteomics, lung, Homo sapiens

Contact List

Yang Mao
contact affiliation	School of pharmaceutical science,Sun Yat-Sen University
contact email	maoyang3@mail.sysu.edu.cn
lab head
Yuqi He
contact affiliation	sun yat-sen university
contact email	heyq57@mail2.sysu.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD051101
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD051101

PRIDE project URI

Repository Record List

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