PXD048365-1

PXD048365 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Inhibitory effect of S-Allylmercaptocysteine on TLR4-mediated inflammation in mammary epithelial cells
Description	Mastitis is an inflammatory disease and negatively affects milk quality and quantity. S-Allylmercaptocysteine (SAMC) inhibits the LPS-induced production of IL-6 and activation of nuclear factor kappaB p65 subunit in cultured mammary epithelial HC11 cells. The global phosphoproteomic analysis revealed that SAMC decreased the phosphorylation level of proteins related to pre-mRNA splicing.
HostingRepository	jPOST
AnnounceDate	2025-01-09
AnnouncementXML	Submission_2025-01-08_07:00:04.549.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jun-ichiro Suzuki
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-09 15:16:49	ID requested
⏵ 1	2025-01-08 07:00:04	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: SAMC, TLR4, Mastitis, inflammation, DIA proteomics, phosphoprotein

submitter keyword: SAMC, TLR4, Mastitis, inflammation, DIA proteomics, phosphoprotein

Contact List

Masahiro Ohtani
lab head
Jun-ichiro Suzuki
contact affiliation	Wakunaga Pharmaceutical Co., Ltd.
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002450/