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PXD046781-2

PXD046781 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFrom birth to bite: the evolutionary ecology of India's medically most important snake venoms
DescriptionVenoms of N. naja and D. russelii individuals of various developmental stages, including neonates (<30 days), juveniles (between 1 to 12 months), and mature individuals (>36 months), were sampled with permission from the state forest department of Karnataka. 226 individuals and 9 clutches were examined, including periodic venom collection (every three months) from the same N. naja and D. russelii juvenile individuals to track ontogenetic changes across time. Freshly collected venoms were flash-frozen in liquid nitrogen, lyophilised and stored at -80° C. Venoms were fractionated using RP-HPLC and SDS-PAGE and subjected to tandem mass spectrometry for toxin identification. The relative abundance of each toxin family were estimated and compared across different developmental stages.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:54:22.403.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKartik Sunagar
SpeciesList scientific name: Naja naja; NCBI TaxID: 35670; scientific name: Daboia russelii; NCBI TaxID: 8707;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-11-08 04:27:35ID requested
12024-08-10 12:41:34announced
22024-10-22 06:54:28announced2024-10-22: Updated project metadata.
Publication List
Senji Laxme RR, Khochare S, Bhatia S, Martin G, Sunagar K, From birth to bite: the evolutionary ecology of India's medically most important snake venoms. BMC Biol, 22(1):161(2024) [pubmed]
10.1186/s12915-024-01960-8;
Keyword List
submitter keyword: Thermofisher orbitrap fusion mass spectrometry, snake venom,Daboia russelii, venom proteomics, Naja naja, ontogeny
Contact List
Dr Kartik
contact affiliationAssistant Professor and Group Leader, Indian institute of Science (IISc), Bangalore
contact emailksunagar@iisc.ac.in
lab head
Kartik Sunagar
contact affiliationAssistant Professor, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India.
contact emailksunagar@iisc.ac.in
dataset submitter
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Dataset FTP location
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