PXD046781 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | From birth to bite: the evolutionary ecology of India's medically most important snake venoms |
Description | Venoms of N. naja and D. russelii individuals of various developmental stages, including neonates (<30 days), juveniles (between 1 to 12 months), and mature individuals (>36 months), were sampled with permission from the state forest department of Karnataka. 226 individuals and 9 clutches were examined, including periodic venom collection (every three months) from the same N. naja and D. russelii juvenile individuals to track ontogenetic changes across time. Freshly collected venoms were flash-frozen in liquid nitrogen, lyophilised and stored at -80° C. Venoms were fractionated using RP-HPLC and SDS-PAGE and subjected to tandem mass spectrometry for toxin identification. The relative abundance of each toxin family were estimated and compared across different developmental stages. |
HostingRepository | PRIDE |
AnnounceDate | 2024-08-10 |
AnnouncementXML | Submission_2024-08-10_12:41:33.655.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Kartik Sunagar |
SpeciesList | scientific name: Naja naja; NCBI TaxID: 35670; scientific name: Daboia russelii; NCBI TaxID: 8707; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-11-08 04:27:35 | ID requested | |
⏵ 1 | 2024-08-10 12:41:34 | announced | |
2 | 2024-10-22 06:54:28 | announced | 2024-10-22: Updated project metadata. |
Publication List
Senji Laxme RR, Khochare S, Bhatia S, Martin G, Sunagar K, From birth to bite: the evolutionary ecology of India's medically most important snake venoms. BMC Biol, 22(1):161(2024) [pubmed] |
10.1186/s12915-024-01960-8; |
Keyword List
submitter keyword: Thermofisher orbitrap fusion mass spectrometry, snake venom,Daboia russelii, venom proteomics, Naja naja, ontogeny |
Contact List
Dr Kartik |
contact affiliation | Assistant Professor and Group Leader, Indian institute of Science (IISc), Bangalore |
contact email | ksunagar@iisc.ac.in |
lab head | |
Kartik Sunagar |
contact affiliation | Assistant Professor, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India. |
contact email | ksunagar@iisc.ac.in |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046781
- Label: PRIDE project
- Name: From birth to bite: the evolutionary ecology of India's medically most important snake venoms