PXD044863-2
PXD044863 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Label free proteomic experiment using M395 sensitive and resistance melanoma cultures to targeted therapy |
Description | In this study, we combined tRNA sequencing, quantitative proteomics and systematic codon usage analysis of translated mRNA to uncover new mechanisms underlying translation reprogramming and therapy resistance in melanoma. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:53:34.590.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD044863 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Najla El-Hachem |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-08-25 10:43:42 | ID requested | |
1 | 2024-08-09 03:00:17 | announced | |
⏵ 2 | 2024-10-22 06:53:35 | announced | 2024-10-22: Updated project metadata. |
Publication List
El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, K, ö, rner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P, Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nat Cell Biol, 26(7):1154-1164(2024) [pubmed] |
10.1038/s41556-024-01439-2; |
10.6019/PXD044863; |
Keyword List
submitter keyword: LC-MS/MS, Melanoma, resistance, Human cells, targeted therapy |
Contact List
Dr Pierre CLOSE, Ph.D. | |
---|---|
contact affiliation | Head of Lab of Cancer Signaling GIGA-institute Université de Liège CHU, B34, Tour GIGA (+2) B-4000 Liège |
contact email | Pierre.Close@uliege.be |
lab head | |
Najla El-Hachem | |
contact affiliation | Laboratory of Cancer Signaling, GIGA-Stem Cells, University of Liège, 4000 Liège, Belgium |
contact email | nelhachem@uliege.be |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044863 |
PRIDE project URI |
Repository Record List
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