PXD044863-2

PXD044863 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Label free proteomic experiment using M395 sensitive and resistance melanoma cultures to targeted therapy
Description	In this study, we combined tRNA sequencing, quantitative proteomics and systematic codon usage analysis of translated mRNA to uncover new mechanisms underlying translation reprogramming and therapy resistance in melanoma.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:53:34.590.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD044863
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Najla El-Hachem
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-25 10:43:42	ID requested
1	2024-08-09 03:00:17	announced
⏵ 2	2024-10-22 06:53:35	announced	2024-10-22: Updated project metadata.

Publication List

El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, K, ö, rner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P, Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nat Cell Biol, 26(7):1154-1164(2024) [pubmed]
10.1038/s41556-024-01439-2;
10.6019/PXD044863;

El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, K, ö, rner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P, Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nat Cell Biol, 26(7):1154-1164(2024) [pubmed]

10.1038/s41556-024-01439-2;

10.6019/PXD044863;

Keyword List

submitter keyword: LC-MS/MS, Melanoma, resistance, Human cells, targeted therapy

submitter keyword: LC-MS/MS, Melanoma, resistance, Human cells, targeted therapy

Contact List

Dr Pierre CLOSE, Ph.D.
contact affiliation	Head of Lab of Cancer Signaling GIGA-institute Université de Liège CHU, B34, Tour GIGA (+2) B-4000 Liège
contact email	Pierre.Close@uliege.be
lab head
Najla El-Hachem
contact affiliation	Laboratory of Cancer Signaling, GIGA-Stem Cells, University of Liège, 4000 Liège, Belgium
contact email	nelhachem@uliege.be
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044863
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044863

PRIDE project URI

Repository Record List

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