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PXD044863-1

PXD044863 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLabel free proteomic experiment using M395 sensitive and resistance melanoma cultures to targeted therapy
DescriptionIn this study, we combined tRNA sequencing, quantitative proteomics and systematic codon usage analysis of translated mRNA to uncover new mechanisms underlying translation reprogramming and therapy resistance in melanoma.
HostingRepositoryPRIDE
AnnounceDate2024-08-09
AnnouncementXMLSubmission_2024-08-09_03:00:16.387.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD044863
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterNajla El-Hachem
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-25 10:43:42ID requested
12024-08-09 03:00:17announced
22024-10-22 06:53:35announced2024-10-22: Updated project metadata.
Publication List
El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, K, ö, rner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P, Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nat Cell Biol, 26(7):1154-1164(2024) [pubmed]
10.1038/s41556-024-01439-2;
10.6019/PXD044863;
Keyword List
submitter keyword: LC-MS/MS, Melanoma, resistance, Human cells, targeted therapy
Contact List
Dr Pierre CLOSE, Ph.D.
contact affiliationHead of Lab of Cancer Signaling GIGA-institute Université de Liège CHU, B34, Tour GIGA (+2) B-4000 Liège
contact emailPierre.Close@uliege.be
lab head
Najla El-Hachem
contact affiliationLaboratory of Cancer Signaling, GIGA-Stem Cells, University of Liège, 4000 Liège, Belgium
contact emailnelhachem@uliege.be
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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