PXD044337-2

PXD044337 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Inducible degradation-coupled phosphoproteomics identifies PP2A-Rts1 as a novel eisosome regulator
Description	We developed and validated a workflow in S. cerevisiae combining auxin-inducible protein degradation with LC-MS/MS phosphoproteomics and used it to identify candidate phosphatase substrates during mitosis, when kinase activity is high. Our results revealed that PP2A-Rts1 influences dephosphorylation of numerous proteins in mitosis, including multiple subunits of the plasma membrane-associated eisosome complex.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:07:16.749.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mark Hall
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	phosphorylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-03 16:15:18	ID requested
1	2023-10-24 06:30:20	announced
⏵ 2	2024-10-22 06:07:17	announced	2024-10-22: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Phosphoproteomics, PP2A, Rts1,Phosphatase, auxin inducible degradation

submitter keyword: Phosphoproteomics, PP2A, Rts1,Phosphatase, auxin inducible degradation

Contact List

Mark Hall
contact affiliation	Purdue University, Department of Biochemistry
contact email	mchall@purdue.edu
lab head
Mark Hall
contact affiliation	Purdue University
contact email	mchall@purdue.edu
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD044337

PRIDE project URI

Repository Record List

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