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PXD044337-1

PXD044337 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInducible degradation-coupled phosphoproteomics identifies PP2A-Rts1 as a novel eisosome regulator
DescriptionWe developed and validated a workflow in S. cerevisiae combining auxin-inducible protein degradation with LC-MS/MS phosphoproteomics and used it to identify candidate phosphatase substrates during mitosis, when kinase activity is high. Our results revealed that PP2A-Rts1 influences dephosphorylation of numerous proteins in mitosis, including multiple subunits of the plasma membrane-associated eisosome complex.
HostingRepositoryPRIDE
AnnounceDate2023-10-24
AnnouncementXMLSubmission_2023-10-24_06:30:20.020.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMarkHall
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListphosphorylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; Orbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-03 16:15:18ID requested
12023-10-24 06:30:20announced
22024-10-22 06:07:17announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Phosphoproteomics, PP2A, Rts1,Phosphatase, auxin inducible degradation
Contact List
MarkHall
contact affiliationPurdue University, Department of Biochemistry
contact emailmchall@purdue.edu
lab head
MarkHall
contact affiliationPurdue University
contact emailmchall@purdue.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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