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PXD035061-1

PXD035061 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma
DescriptionSerine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Here, we found that R236 methylation of PHGDH promotes its activity and stimulates serine synthesis in hepatocellular carcinoma.
HostingRepositoryiProX
AnnounceDate2022-07-04
AnnouncementXMLSubmission_2022-07-03_23:54:50.341.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKui Wang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListmonomethylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-03 23:54:44ID requested
⏵ 12022-07-03 23:54:50announced
22023-03-01 19:00:54announced2023-03-02: Update publication information.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: PHGDH, arginine methylation
Contact List
Canhua Huang
contact affiliationSichuan University
contact emailhcanhua68@163.com
lab head
Kui Wang
contact affiliationSichuan University
contact emailwangkui416@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI

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