PXD027382-2

PXD027382 is an original dataset announced via ProteomeXchange.

Title	Adenylyl cyclase 3 deficiency results in the dysfunction of blood-testis barrier during mouse spermiogenesis
Description	Human infertility has become a medical and social health problem globally. Mice deficient in type 3 adenylyl cyclase (AC3), a key enzyme that synthesizes cyclic adenosine monophosphate (cAMP), develop male infertility but its underlying molecular mechanisms are still unknown. Here, we performed label-free quantitative (LFQ) proteomics study to identify testicular differentially expressed proteins (DEPs) and their respective biological processes.
HostingRepository	iProX
AnnounceDate	2021-07-19
AnnouncementXML	Submission_2023-12-06_23:59:50.460.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tingrong Chen
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-18 22:46:30	ID requested
1	2021-07-18 22:52:51	announced
⏵ 2	2023-12-06 23:59:51	announced	2023-12-07: Update information.

Chen T, Zhou Y, Liu X, Liu Y, Yuan J, Wang Z, Adenylyl cyclase 3 deficiency results in dysfunction of blood-testis barrier during mouse spermiogenesis. Theriogenology, 180():40-52(2022) [pubmed]

submitter keyword: AC3, proteome, spermaotgenesis, testis, male sterility

Zhenshan Wang
contact affiliation	Hebei University
contact email	zswang@hbu.edu.cn
lab head
Tingrong Chen
contact affiliation	Hebei University
contact email	chentingrong1990@163.com
dataset submitter

iProX dataset URI