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PXD025780-1

PXD025780 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics characterization of extracellular vesicles derived from fermented food industry by-product: looking for new potential delivery vectors
DescriptionIn the last decade, the interest in extracellular vesicles (EVs) as safe and biocompatible nano-transporters has risen dramatically, as these nanoparticles can be used to increase the delivery efficiency rate and reduce secondary effects. However, the difficulty for its obtention in large quantities represents a major drawback for its utilization. Also, EVs are currently mainly derived from immortalized cell lines, which may arise safety problems when administered to humans. Hence, the shift from cell lines to safer EVs sources would suppose a step ahead for its use as delivery vectors in the biotechnology and biomedical research fields. Here, we provide proteomics characterization of EVs isolated by molecular weight cut-off filtration (MWCO) from four different fermented food industry by-products (FFIBPs), including: i) yogurt whey (named as milk in the raw data files), symbiotic culture of bacteria and yeast (SCOBY) from kombucha fermented tea (named as Com in the raw data files), wine pomace (named as Wine in the raw data files) and brewer spend yeast (named as beer in the raw data files).This proteomics characterization will provide key information about composition of by-product derived EVs (BP-EV) uncovering a safe and sustainable EVs source with potential as functional EVs delivery vectors.
HostingRepositoryPRIDE
AnnounceDate2022-04-27
AnnouncementXMLSubmission_2022-04-27_09:02:27.642.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAida Serra
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationListiodoacetamide derivatized residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-05-04 01:42:19ID requested
12022-04-27 09:02:27announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: EVs, food industry by-products, circular economy, extracellular vesicles, food-derived vesicles, nanotransporters, nanovectors, molecular weight cut-off, LC-MS, proteomics
Contact List
Aida Serra, PhD.
contact affiliationIMDEA-Food Research Institute +Pec Proteomics Campus of International Excellence UAM+CSIC 8 Crta. Canto Blanco, Madrid, 28049, Spain Email: aida.serra@imdea.org Tel: (+34) 917278100
contact emailaida.serra@imdea.org
lab head
Aida Serra
contact affiliationIMDEA-Food Research Institute, +Pec Proteomics, Campus of International Excellence UAM+CSIC, Old Cantoblanco Hospital, 8 Crta. Canto Blanco, Madrid, 28049, Spain.
contact emailaida.serra@imdea.org
dataset submitter
Full Dataset Link List
Dataset FTP location
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