PXD024596-1
PXD024596 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Dengzhan shengmai brian mitochondrial proteome |
Description | To improve our understanding on neuroprotective effect, afford by DZSM on CCH, we constructed two independent quantitative mitochondrial proteome and phospho-proteome experiment for dissecting the therapy of DZSM, data shows that DZSM attenuated CCH by regulating mitochondrial-mediated pathway (mainly TCA cycle and OXPHOS). The differentially expressed mitochondrial proteins identified such as Atp5o, Cox4il and Dlat were related to mitochondrial TCA cycle and OXPHOS, which were further validated by parallel reaction monitoring (PRM) technology. |
HostingRepository | iProX |
AnnounceDate | 2021-03-08 |
AnnouncementXML | Submission_2021-03-09_00:07:36.821.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hao Zheng |
SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
ModificationList | phosphorylated residue; TMT6plex reporter fragment |
Instrument | Orbitrap Fusion Lumos; TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-03-09 00:06:43 | ID requested | |
⏵ 1 | 2021-03-09 00:07:37 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Dengzhan shengmai brian mitochondrial proteome |
Contact List
Jinlan Zhang | |
---|---|
contact affiliation | Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College |
contact email | zhangjl@imm.ac.cn |
lab head | |
Hao Zheng | |
contact affiliation | institute of materia medica, Chinese academy of medical science |
contact email | 595113331@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |