PXD024130-1

PXD024130 is an original dataset announced via ProteomeXchange.

Title	The proteome of trained immunity
Description	Different studies in the last decade have shown that cells of the innate immune system, such as monocytes and macrophages, can present non-specific memory and enhanced responsiveness to secondary stimulation after challenge with several stimuli, such as beta-glucan or BCG, what has been termed trained immunity. These changes are posible thanks to deep metabolic and epigenetic reprogramming in these cells, which allows the aforementioned enhanced responsiveness after subsequent stimulation. In this project we intend to study the changes in proteome upon induction of trained immunity or tolerance in monocytes.
HostingRepository	PRIDE
AnnounceDate	2023-07-20
AnnouncementXML	Submission_2023-07-20_14:53:50.754.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AmirBanaei-Esfahani
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-11 02:36:17	ID requested
⏵ 1	2023-07-20 14:53:51	announced

Holstein T, Kistner F, Martens L, Muth T, PepGM: a probabilistic graphical model for taxonomic inference of viral proteome samples with associated confidence scores. Bioinformatics, 39(5):(2023) [pubmed]

submitter keyword: Human, Monocytes, Immunity, Trained, Proteomics

Prof. Dr. RuediAebersold
contact affiliation	ETH Zurich
contact email	aebersold@imsb.biol.ethz.ch
lab head
AmirBanaei-Esfahani
contact affiliation	ETH Zurich
contact email	amir.banaei@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD024130

PRIDE project URI

• PRIDE
  1. PXD024130
     1. Label: PRIDE project
     2. Name: The proteome of trained immunity