PXD024096 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Investigation of the host response of naïve Atlantic salmon gill to repeat inoculation with Paramoeba perurans |
Description | In aquaculture, recurrence rates of Amoebic Gill Disease (AGD), caused by the ectoparasite Paramoeba perurans (P. perurans) are high and no prophylactic strategies exist for disease prevention. In this study, Atlantic salmon (Salmo salar) were initially inoculated with P. perurans and following the development of amoebic gill disease were treated with fresh water immersion on day 21 and day 35 post inoculation. Fish were re-inoculated following a negative Q-PCR analysis for the presence of P. perurans. The gill host immune response was investigated at 7, 14 and 18 days post re-inoculation. Differential proteome expression of immune related proteins was assessed by comparison of each time point against naïve controls. In the gill, some proteins of the innate immune system were expressed in response to gill re-colonisation by P. perurans, while no features of adaptive immunity were found to be differentially expressed. Many of the proteins identified are novel in the context of AGD and their expression profiles suggest that their roles in the response to disease development and progression in single or multiple infections warrant further investigation. |
HostingRepository | PRIDE |
AnnounceDate | 2021-05-12 |
AnnouncementXML | Submission_2021-05-12_01:00:15.063.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Eugene Dillon |
SpeciesList | scientific name: Salmo salar (Atlantic salmon); NCBI TaxID: 8030; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-02-09 10:40:23 | ID requested | |
⏵ 1 | 2021-05-12 01:00:15 | announced | |
2 | 2021-05-12 04:12:17 | announced | 2021-05-12: Updated project metadata. |
Publication List
Keyword List
submitter keyword: salmon,gill, proteomics |
Contact List
Michelle McCormack |
contact affiliation | Marine and Freshwater Research Centre, Galway Mayo Institute of Technology, Dublin Road, Galway, Ireland, H91 TRNW |
contact email | michelle.mccormack@gmit.ie |
lab head | |
Eugene Dillon |
contact affiliation | UCD |
contact email | eugene.dillon@ucd.ie |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD024096
- Label: PRIDE project
- Name: Investigation of the host response of naïve Atlantic salmon gill to repeat inoculation with Paramoeba perurans