PXD020732 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity |
| Description | Actin was acetylated on lysine residues with acetic anhydride to determine its impaction on the contractile properties of the thin filaments including, actin's ability to undergo crossbridge cycling with myosin, actin's affinity for tropomyosin, and the impact of actin acetylation on calcium regulated thin filament activation |
| HostingRepository | PRIDE |
| AnnounceDate | 2020-09-04 |
| AnnouncementXML | Submission_2020-09-06_23:55:21.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD020732 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | D. Brian Foster |
| SpeciesList | scientific name: Oryctolagus cuniculus; NCBI TaxID: 9986; |
| ModificationList | acetylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2020-08-05 03:09:56 | ID requested | |
| 1 | 2020-09-04 03:50:30 | announced | |
| ⏵ 2 | 2020-09-06 23:55:22 | announced | 2020-09-07: Updated publication reference for PubMed record(s): 32873710.
2020-09-07: Updated publication reference for DOI(s): 10.1074/jbc.RA120.015277. |
| 3 | 2023-11-14 08:51:44 | announced | 2023-11-14: Updated project metadata. |
Publication List
| Schmidt W, Madan A, Foster DB, Cammarato A, Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity. J Biol Chem, 295(46):15527-15539(2020) [pubmed] |
| 10.1074/jbc.RA120.015277; |
Keyword List
| submitter keyword: actin, lysine acetylation, tropomyosin, thin filament, myosin, in vitro motility |
Contact List
| Brian Foster |
|---|
| contact affiliation | Johns Hopkins School of Medicine, Division of Cardiology |
| contact email | dbrianfoster@jhmi.edu |
| lab head | |
| D. Brian Foster |
|---|
| contact affiliation | Johns Hopkins University School of Medicine |
| contact email | dbrianfoster@jhmi.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD020732 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020732
- Label: PRIDE project
- Name: Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity
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