PXD020018 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of SAMD9 and SAMD9L interactome in HEK293T cells |
Description | Recently, heterozygous germline mutations were identified in sterile alpha motif (SAM) domain-9 (SAMD9) and its paralog, SAMD9-like (SAMD9L) in children with monosomy 7 mediated MDS. Expression of SAMD9 and SAMD9L is induced by interferons and other inflammatory stimuli and causes reduced cell division and cell growth and most pathogenic mutations found in patients dramatically enhance these effects. The goal of this project is to identify the interactome of SAMD9 and SAMD9L to better understand their role in cell cycle and proliferation regulation |
HostingRepository | PRIDE |
AnnounceDate | 2021-03-24 |
AnnouncementXML | Submission_2021-03-24_10:08:42.252.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Vishwajeeth Pagala |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | biotinylated residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-25 16:09:03 | ID requested | |
⏵ 1 | 2021-03-24 10:08:42 | announced | |
2 | 2021-03-24 23:28:25 | announced | 2021-03-25: Updated project metadata. |
3 | 2021-03-24 23:30:35 | announced | 2021-03-25: Updated project metadata. |
Publication List
Keyword List
submitter keyword: SAMD9 |
SAMD9L |
pediatric MDS |
proteomics |
Contact List
Jeffery Klco |
contact affiliation | Associate Member, Hematological Malignancies Program St. Jude Children's Research Hospital Memphis-TN UA |
contact email | jeffery.klco@stjude.org |
lab head | |
Vishwajeeth Pagala |
contact affiliation | St. Jude Children's Research Hospital |
contact email | vishwajeeth.pagala@stjude.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD020018 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020018
- Label: PRIDE project
- Name: Identification of SAMD9 and SAMD9L interactome in HEK293T cells