PXD018597-2
PXD018597 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity |
Description | In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resistance in PTEN-loss patients. |
HostingRepository | iProX |
AnnounceDate | 2020-04-16 |
AnnouncementXML | Submission_2020-11-24_22:05:09.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yi Huang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-04-16 04:54:50 | ID requested | |
1 | 2020-04-16 04:58:15 | announced | |
⏵ 2 | 2020-11-24 22:05:10 | announced | 2020-11-25: Update publication information |
Publication List
Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, Song L, Wang Y, Li Q, Shan B, Jiang Y, Li H, Shao Z, Kroemer G, Zhang H, Bai L, Jin T, Wang C, Ma Y, Cai Y, Ding C, Liu S, Pan Y, Jiang W, Zhou R, Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nat Cell Biol, 22(6):716-727(2020) [pubmed] |
Keyword List
submitter keyword: Myeloid PTEN, chemotherapy, NLRP3 inflammasome |
Contact List
Rongbin Zhou | |
---|---|
contact affiliation | University of Science and Technology of China |
contact email | zrb1980@ustc.edu.cn |
lab head | |
Yi Huang | |
contact affiliation | University of Science and Technology of China |
contact email | hy527@mail.ustc.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |